Yes, a dire mace, unless for some reason changed here, will count as a medium sized weapon in the primary hand and a light weapon in the offhand.
You can liken this to a warhammer in the primary hand and a standard mace in the offhand. That is, with all two weapon fighting feats (ambi, twf, and itwf), you will be looking at a -2/-2 to AB on the primary and secondary hands. This is opposed to the -4/-8 AB penalty you would face without ambi and twf.
Improved two weapon fighting (itwf) will also apply in giving you an extra offhand attack at the normal -5 penalty.